LCN2 and nasopharyngeal carcinoma: To assess the effect of LCN2 levels on NPC cells, LCN2 expression was down-regulated by the transfection of siRNA targeting LCN2 (siLCN2) in the HONE-1 cells; conversely, LCN2 expression was up-regulated by the transfection of LCN2-expressing plasmids in the NPC-BM cells.