For example, the mutation c.518T > G (Leu173Arg) in UGT1A9 was observed in five CCLE cell lines (JHOM1, LUDLU1, CAPAN1, TCCSUP and HT29) that were derived from five different types of cancers (ovary cancer, non-small cell lung cancer, pancreatic cancer, bladder cancer and colorectal cancer, respectively) (Table S5). This evidence concerns the gene UGT1A9 and colorectal cancer.