Among 33 tumors, ACY1 expression was markedly higher in 22 types of tumors compared with adjacent noncancerous samples, including adrenocortical carcinoma, bladder urothelial carcinoma, breast invasive carcinoma, cervical squamous cell carcinoma and endocervical adenocarcinoma, lymphoid neoplasm diffuse large B-cell lymphoma, lung adenocarcinoma, and lung squamous cell carcinoma (Figure 2A). The gene discussed is ACY1; the disease is adrenal cortex carcinoma.