KLRD1 and neoplasm: Since Hsp70-primed CD3−/CD94+ NK cells play a critical role in recognizing and killing membrane Hsp70-positive tumor cells [15], the immunophenotype of NK cells and other peripheral blood lymphocyte subpopulations was comparatively assessed together with the circulating Hsp70 levels in patients with NSCLC in UICC stages IIIA, IIIB, and IV.