In this study, we evaluated both RAD51 and pRPA32 (a marker of DNA end resection, a distinct step involved in the initiation of HR activity) and demonstrate that the levels of both these proteins are high in EAC (OE19, FLO-1), colon cancer (HCT116, HT29) and breast cancer (MCF7) and cell lines. Here, RAD51 is linked to colonic neoplasm.