A recent paper demonstrated that CTC diameter is significantly different among several cancer types and that EpCAM-selected cytokeratin-positive CTCs in women with breast cancer have smaller median diameter (12.4 μm) compared to tumor cells detected in the liquor (13.4 μm) and to in vitro cultured cell lines (18.4 μm) [103]. This evidence concerns the gene EPCAM and breast carcinoma.