This paper detected the prognostic value of CD73 in pan-cancer and found that elevated CD73 was associated with poor OS in patients with ACC, BRCA, CESC, HNSC, KIRP, LGG, LIHC, LUAD, LUSC, MESO, STAD, UVM, KICH, PAAD, and TGCT. This evidence concerns the gene NT5E and cancer.