Our data showed that the top three cancers were BLCA, BRCA, and COAD, where CD73 expression in the tumor microenvironment is associated with infiltration of immune cells, including B cell, CD4 and CD8 T cell, dendritic cell, macrophage, and neutrophil (Figure S6; p < 0.05). Here, CD8A is linked to bladder transitional cell carcinoma.