In line with the pro-apoptotic microenvironment of low-risk MDS and the anti-apoptotic features of high-risk MDS, BM cells in RA patients overexpress TNFR1 [Figure 3], while TNFR2 expression is notable in RAEB patients [Figure 4], [116]. Here, TNFRSF1A is linked to myelodysplastic syndrome.