ERBB2 and breast cancer: When examining the prognostic significance of CDCA5 mRNA expression in various molecular subtypes, our results showed that luminal A (p < 0.001; Figure S2A), Luminal B (p = 0.005; Figure S2B), and Normal like (p = 0.002; Figure S2C) BC patients with high CDCA5 mRNA expression had significant association with poor patients’ survival compared to patients who had low CDCA5 mRNA expression but not TNBC nor HER2+ classes.