Together, CDCA5 may have an important role in the upregulation of N-cadherin and EGFR and concomitant downregulation in E-cadherin is a key step in BC progression and is associated with that activation of the β-catenin; LEF/TCF regulation of vimentin expression, which has previously been shown to promote BC invasion and metastasis [3,39]. Here, EGFR is linked to breast cancer.