CD4 and melanoma: Consistent with the findings obtained from melanoma, a favorable infiltration of immune response lymphocytes (e.g., activated CD4/CD8 T cells, resting NK cells, and M1 macrophages) (all p < 0.05; Figure S7A,B), an elevated enrichment of interferon γ/α responses (Figure S7C), and a decreased enrichment of immune-inhibited pathways (e.g., TGFβ and EMT signals) (Figure S7C) were noticed in FASN mutated NSCLC samples.