To explore the possible molecular mechanisms of the relationships of the decreasing level of lysoPC (16:0) with tumor metastasis, we performed network prediction of LCAT, GDPD1, TGFB1 (TGF-β), HIF1A (hypoxia-inducible factor 1 (HIF1-α)), COL1A1, ACTA2, and ENG with proteins that were related to the above seven proteins in the STRING database. The gene discussed is HIF1A; the disease is neoplasm.