GAS5 and head and neck cancer: Further, in a study with 41 patients who underwent radical chemoradiotherapy, lncRNA HOTAIR, lincRNA-p21, and GAS5 expression were measured in their plasma samples and the results demonstrated that GAS5 showed significant association with the treatment response, whereas HOTAIR lincRNA-p21 levels in plasma did not show any conclusive results in head and neck cancers [111,112].