BCR and diffuse large B-cell lymphoma: A further classification of DLBCL, independent of the cell-of-origin subtypes, relates to their metabolic signature: OXPHOS-DLBCL with upregulated mitochondrial metabolism; BCR-DLBCL with increased expression of cell-cycle regulatory genes; with a third DLBCL subset characterized by markers of an ongoing host inflammatory/immune response—HR-DLBCL [56].