Furthermore, MYC translocations are a poor prognostic factor in DLBCL in association with BCL2 and/or BCL6 translocations, and MYC re-arrangements are also a driver of high-grade transformation in follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL) [43]. The gene discussed is BCL2; the disease is B-cell chronic lymphocytic leukemia.