TIMP3 and cancer: The top 10 most altered proteins are presented in Figure 1D. The majority of proteins, listed in Figure 1D, are part of cancer-relevant pathways such as proliferation (e.g., STX4, SCIN, TXNRD1), apoptosis (e.g., ESPL1, CD44, ATP2 A3, RALB, SCIN, TIMP3) and migration (e.g., S100 P, CD44, STX4, LCP1).