The top 10 most altered proteins are presented in Figure 1D. The majority of proteins, listed in Figure 1D, are part of cancer-relevant pathways such as proliferation (e.g., STX4, SCIN, TXNRD1), apoptosis (e.g., ESPL1, CD44, ATP2 A3, RALB, SCIN, TIMP3) and migration (e.g., S100 P, CD44, STX4, LCP1). The gene discussed is TXNRD1; the disease is cancer.