Eight variables were associated with a shorter OS1 in univariate analysis: older age (p = 0.001), multilobar tumor (p = 0.008), unmethylated MGMT (p < 0.001), short period of TMZ consolidation treatment (p < 0.001), short PFS1 (p < 0.001), short or intermediate TFR (vs. long TFR) (p < 0.001), short PFS2 (p < 0.001) and the supportive care option (p < 0.001) (Table S1). This evidence concerns the gene MGMT and neoplasm.