EGFR and cancer: For the JHU029 cells, some deregulated genes belong to the tetraspanin (TSPAN) family and the melanoma antigen gene (MAGE-I) family of the tumour-specific antigens, whose expression is deregulated in cancer; for the HTB-43 cells, a large number of deregulated genes are associated and interact with the EGFR-associated pathways, and for the CCL-138 cells, some genes belong to the histone family [44,47,48].