Meanwhile, the cell component estimated based on the gene expression profile showed that natural killer (NK), terminal effector CD8 + (CD8_TE) and terminal effector CD4 + (CD4_TE) cells were enriched in the SCLC group and platelets, type-2 T-helper cells (Th2), CD4_TE and monocytes were related to the patient’s prognosis. This evidence concerns the gene CD4 and small cell lung carcinoma.