TP53 and cancer: Ginger and its phytoconstituents have also been effective against other cancers such as ovarian [158], colon [146], non-small lung [159], lung [159], gastric adenocarcinoma [160], melanoma [161], and cervical [162] by modulating NF-κB, p21, ERK1/2, p38, p53, Wnt/ß-catenin, and AMPK.