In the tumour stage, GNAS gene mutation was recorded highest in the late stage at 67.9% (95% CI: 0.497–0.843) than the early stage, while in tumour location, the colon has the highest GNAS gene mutation of 50.5% (95% CI: 0.332–0.676) for the tumour located in the colon. The gene discussed is GNAS; the disease is neoplasm.