CYCS and melanoma: It was, moreover, demonstrated that the peptide-induced apoptosis in SBcl-2 or A375 melanoma cells occurred due to the specific interaction with the PS exposed by their membranes and the formation of a bioactive structure to enter the cell and reach the Golgi upon hours of incubation, followed by mitochondrial swelling, cytochrome C release, lipid trafficking, apoptotic blebbing and finally apoptotic cell death [12,13].