As with Th17 cells, tumor-infiltrating γδT cells do not exclusively produce IL-17 but are also considered as an important source of cytokines such as IL-8, GM-CSF, and TNFα, enabling them, in particular, to recruit polymorphonuclear myeloid-derived suppressor cells [78] into the tumor tissue and, thus, to contribute significantly to the establishment of an immunosuppressive and tumor-promoting milieu [14]. The gene discussed is CXCL8; the disease is neoplasm.