ccRCC: Vimentin(+), CAIX(+) membranous, PAX8(+), CK7(−), 34βE12(−), GATA3(−), p63(−)pRCC: Vimentin(+), CAIX(−), PAX8(+), CK7(focal/-), 34βE12(−), GATA3(−), p63(−)chRCC: Vimentin(+), CAIX(−), PAX8(+), CK7(+), 34βE12(−), GATA3(−), p63(−)MTSC: Vimentin(+), CAIX(−), PAX8(+), CK7(+), 34βE12(variable), GATA3(−), p63(−)Urothelial: Vimentin(+), CAIX variable/mostly(−), PAX8 mostly(−), CK7(+), 34βE12(+), GATA3(+), p63(+)Sarcoma: Vimentin(+), CAIX(−), PAX8(−), CK7(−), 34βE12(−), GATA3(−), p63(−). The gene discussed is PAX8; the disease is nonpapillary renal cell carcinoma.