On the contrary, IL8, together with IL6 and TNFα, were significantly upregulated in SOD1G93A MNs co-cultured with hMSCs compared with wildtype MNs co-cultured with hMSCs, suggesting that hMSCs do not alleviate ALS-related inflammatory mechanisms within this experimental context. This evidence concerns the gene CXCL8 and amyotrophic lateral sclerosis.