A nomogram, integrating clinicopathological variables including age, sex, ICIs categories, TMB, and FGFR1/2/3/4 status, was formulated to predict the 1-year OS, 3-year OS and 5-year OS of those ICIs-treated melanoma patients based on multivariable analysis (Figure 5A). The gene discussed is FGFR1; the disease is melanoma.