In terms of liver samples from Mus musculus, 10 pathways were found to be significantly associated with risk scores in the nilotinib group, including FC epsilon RI, type II diabetes mellitus, B-cell receptor, apoptosis, insulin, natural killer cell mediated cytotoxicity, FC gamma R mediated phagocytosis, mTOR, chemokine, and T-cell receptor signaling pathways (Figure 9 and Table 3). Here, INS is linked to type 2 diabetes mellitus.