After adjustment by multivariate analysis, ALDH2*2 (OR: 2.643; 95% CI, (1.286, 5.434); P = 0.008) and hypertension (OR: 2.012; 95% CI, (1.011, 4.001); P = 0.046) remained significant factors. The gene discussed is ALDH2; the disease is hypertensive disorder.