ESR1 and breast carcinoma: Therefore, we selected ER-positive breast cancer MCF-7 cells and used RNA-seq to analyze the gene expression differences of breast cancer cells treated with Chidamide, and performed functional enrichment of potential genes to clarify the drug targets of Chidamide for the treatment of breast cancer, laying the foundation for the treatment of malignant tumors, especially breast cancer, and the development of new drugs.