Also, in patients with septic shock, a higher percentage (64%) of CD19+CD23+ at ICU admission appears to be a reliable biomarker of good prognosis, while within 24 h of diagnosis, the combination of immature/transitional B cells and resting memory B cells counts is significantly more predictive of 60-day mortality in sepsis than commonly used critical illness scores (Monserrat et al., 2013; Dong et al., 2020). This evidence concerns the gene CD19 and Sepsis.