MUC1 and melanoma: Pouniotis et al. (2006) and Pouniotis et al. (2016) demonstrated that penetratin in conjunction with cytotoxic T lymphocyte epitopes derived from ovalbumin or mucin-1 tumor-associated antigens could stimulate CD4+ and CD8+ T cells in vitro. Also, T cell-mediated cytokine release limited B16.OVA melanoma cell proliferation in vivo.