It was discovered that liver cancer tissues had lower levels of ANGPTL6, CFP, CLEC1B, CLEC4G, CLEC4M, COLEC10, CRHBP, CXCL12, DNASE1L3, FCN2, FCN3, GSTZ1, LCAT, NAT2, OIT3, RSPO3, VIPR1, STAB2, ECM1, and GPR128 expression compared to normal liver cells. This evidence concerns the gene CXCL12 and liver cancer.