Consequently, these findings imply that FCN2 may suppress the HCC tumor immune response by favorably regulating neutrophils (19, 20), eosinophils (21), NK cells (22–24), Tcm (25), and DCs (26–28) and negatively regulating Th2 (29–31) in tumors. This evidence concerns the gene FCN2 and hepatocellular carcinoma.