Totally, ING5 expression was detected in 40.6% (400/986) of cancer tissues, among which ING5 was more frequently expressed in colorectal (56.3%), breast (79.9%) and endometrial (50.0%) cancers, and less in pancreatic cancer (22.6%) and HCC (14.5%) (Yang et al., 2019). Here, ING5 is linked to familial pancreatic carcinoma.