MAPT and early-onset autosomal dominant Alzheimer disease: Lately a tau protein immunosensor based on manganese sulphide (MS) graphene oxide (GO) and PANI (MnS/GO/PANI) with magnetite-incorporated gold nanoparticles immunosensor has been developed for the electrochemical detection of tau protein which exhibited superior selectivity, sensitivity, and environmental compatibility.42 The sensor demonstrated the a detection limit of 1.0 × 10−14 M which could be utilized for diagnosis of Alzheimers disease.