Patients with a CD4 count ≤ 200 cells/μL (vs. CD4 > 200 cells/μL, IRR for all-cause and ADE-related hospitalizations: 3.95 and 7.45, respectively) or a VL > 50 copies/mL (vs. VL ≤ 50 copies/mL, IRR: 1.45 and 1.64, respectively) had a higher risk of all-cause and ADE-related hospitalizations. The gene discussed is CD4; the disease is acute disseminated encephalomyelitis.