RORA and memory: The decreased expression of RORA impacts the regulation of its target genes in ASD-afflicted individuals (several of which are ASD-relevant genes) and is associated with the pathobiology of ASD, such as with decreases in neuronal differentiation and survival, poorer synaptic transmission and neuroplasticity, diminished cognition and spatial learning, memory impairment, and disrupted development of the cortex and cerebellum [36].