ATG5 and fungal keratitis: In fungal keratitis, miR-665-3p overexpression can not only increase the production of IL-1β but also inhibit autophagosome formation (i.e., impaired autophagic flux) by targeting autophagy-related (ATG) 9 A, ATG14, ATG4B and ATG5 genes, among which ATG5 is most closely related to autophagosome formation[69].