The most common TRAEs (≥10%) were diarrhea (71.9%), serum creatinine elevated (45.3%), AST elevated (39.1%), nausea (37.5%), vomiting (35.9%), ALT elevated (34.4%), γ-glutamyl transpeptidase (γ-GGT) elevated (32.8%), hyperuricemia (31.25%), weight loss (28.1%), abdominal pain (26.6%), hypertriglyceridemia (23.4%), proteinuria (21.9%), appetite decreased (18.75%), hypoalbuminemia (17.2%), abdominal pain upper (17.2%), hyperglycemia (15.6%), hypercholesterolemia (12.5%), and conjugated bilirubin elevated (10.9%). This evidence concerns the gene GPT and hyperuricemia.