As for PFI, the plots showed that high expression of STEAP3 may be a prognostic risk factor for ACC, GBM, HNSC, KIRC, KIRP, LGG, LUSC, PAAD and UVM, while may be a protective factor for PRAD (Fig. 2C). The gene discussed is STEAP3; the disease is pancreatic adenocarcinoma.