PRTN3 and acute myeloid leukemia: AML-AP1 expressed Prtn3, which is a marker of the monocytic lineage22, along with Jun and Fos, which comprise the AP1 transcription complex38, as well as Dusp1, which are all part of the MAP-kinase signaling pathway (https://www.kegg.jp/pathway/mmu04010) and are associated with cell proliferation.