Platelets can be applied in other immune‐associated diseases.[53] In 2020, Z. Gu et al.[53a] further developed PD‐L1‐engineered platelets to modulate the PD‐1/PD‐L1 signal axis for protecting pancreatic β cell in new‐onset type 1 diabetes mice. This evidence concerns the gene CD274 and type 1 diabetes mellitus.