CD274 and neoplasm: In addition to the aforementioned wound‐targeting ability, platelets could also interact with and be activated by tumor cells or circulating tumor cells.[44] It is reported that platelets can induce dendritic cells (DCs) maturation and boost the immune response of T cells.[45] In 2017, Z. Gu's team[46] was pioneered to conjugate PDL1, a kind of immune checkpoint inhibitor antibody, on the surface of platelets for preventing the recurrence and metastasis of tumor after surgery.