CFHR1 and Parkinson disease: Interestingly, all the differentially expressed inflammation-related proteins, complement proteins (C1Q, C9, C1B, C1C, C4B, C4A, CFHR1, and C1S), and interferon-gamma receptor 1 were increased, clearly showing that the activated complement proteins are one of the potential main causative factors of PD (supplemental Data S2).