ARG2 expression by IHC was cytoplasmic, dot-like or coarsely granular in nature (Supplementary Figure S2, available at https://doi.org/10.1016/j.esmoop.2022.100636), with 50% (11 of 22) of BCs and 63.6% (14 of 22) of BCBMs being defined as ARG2 positive (>1% ARG2 staining of tumour cells).22 Here, ARG2 is linked to neoplasm.