Immunohistochemical characterization of six tumor regions was done for ALK and markers of lung adenocarcinoma (NKX2.1), epithelial (E‐cadherin, pan‐cytokeratin, and cytokeratin 18) and mesenchymal (vimentin) phenotypes, tumor vasculature (CD31), and basement membrane organization (collagen type IV). The gene discussed is CDH1; the disease is lung adenocarcinoma.