ACE2 and COVID-19: Syrian hamsters (Mesocricetus auratus) rapidly developed into a popular model, as they naturally express ACE2 residues that recognize the SARS-CoV-2 spike protein, making them susceptible to SARS-CoV-2 infection and recapitulating many characteristic features as seen in patients with a moderate, self-limiting course of the disease such as specific patterns of respiratory tract inflammation, vascular endothelialitis, and age dependence mimicking transmission and different courses of the wide spectrum of COVID-19 manifestations in humans [12,13,20,21,22,23].