These data are important, since with the time of use of ART, the levels of CD4 T lymphocytes increase and the viral load decreases, but as this happens, the levels of lipids increase, showing that, in general, ART is effective and safe, but that individuals with a predisposition to metabolic diseases associated with nutritional changes need to be monitored so that they do not develop serious diseases, such as heart disease. This evidence concerns the gene CD4 and heart disorder.