To investigate the possible association of these SNPs with SARS-CoV-2 infection, we sequenced the IFITM3 locus of 203 hospitalized COVID-19 patients, which included 133 mild cases (65.5%), 43 severe cases (21.2%), and 27 deaths (13.3%) (Figure 4B). The gene discussed is IFITM3; the disease is COVID-19.