Pertussis-containing vaccines include whole-cell pertussis vaccines and acellular pertussis vaccines, which contain one or more pertussis antigens, including pertussis toxoid (PT), filamentous hemagglutinin (FHA), pertactin (PRN), and fimbrial proteins 2 (FIM2) and 3 (FIM3) [71]. The gene discussed is CIAO3; the disease is pertussis.