The cytokines tumor necrosis factor-alpha, interleukin-8, interleukin-6, and interleukin-1 beta were detected in the airway secretions of children infected with RSV and Mycoplasma pneumonia, which may act as a double whammy of respiratory pathogens and correlate with severe pathogenesis [171,172,173,174]. Here, IL6 is linked to Mycoplasma pneumoniae pneumonia.