The 21-exon solute carrier family 26 member 3 (SLC26A3) gene is mapped to chromosome 7q31 and encodes for the chloride/bicarbonate exchanger, also known as down regulated in adenoma (DRA), a transmembrane protein localized mainly to the apical side of the mucosa in the ileum and proximal colon (Byeon et al. 1996). This evidence concerns the gene SLC26A3 and adenoma.