AMELX and dental caries: Interestingly, the C allele of the SNP in AMELX (rs17878486) was associated with a higher risk of dental caries in primary dentition (p = 0.015, OR = 2.05, 95% CI 1.09–3.84), while the opposite effect was observed in permanent dentition (p = 0.011, OR = 0.70, 95% CI 0.51–0.94, Table 2).