Thus, the deranged innate immune response that can occur in severe COVID-19 patients might also contribute to amplifying the cytokine storm that follows the infection, indicating that a possible effective adjuvant therapy for the treatment of COVID-19-induced pneumonia could be the synergic inhibition of the proinflammatory IL-1β combined with the administration of IFN-λ [26]. The gene discussed is IL1B; the disease is COVID-19.